Featured Categories
Browse All Categories
Featured Product
Elevate your wellness routine with our top-rated peptides, designed to enhance your health journey.
Featured Collections
Browse All Collections
Discover Lines
Explore our most popular lines, curated to elevate your wellness journey.
Featured Knowledge
Expert Knowledge
Explore our scientifically-backed content for optimal health and wellness insights.

Key Ingredients
5-Hydroxytryptophan
Not sure about the right dosage?
Use our Peptide Dosage Calculator for optimal application
Main Information
5-HTP is a natural serotonin precursor extracted from the seeds of Griffonia simplicifolia. It helps support mood balance, reduce anxiety, and promote restful sleep by naturally increasing serotonin levels in the brain.
Scientific Background
5-HTP (5-Hydroxytryptophan) is a naturally occurring amino acid and metabolic intermediate in the biosynthesis of serotonin. It is derived from the seeds of Griffonia simplicifolia and has been widely studied for its role in mood regulation, appetite control, and sleep quality. Once ingested, 5-HTP crosses the blood-brain barrier and is rapidly converted to serotonin, influencing emotional balance and circadian rhythm (Birdsall, 1998). Clinical research has shown that 5-HTP supplementation may support individuals with mild depressive symptoms, stress-related cravings, or disrupted sleep patterns (Shaw et al., 2002). Its non-stimulant profile makes it especially suitable for evening use or as part of a holistic approach to serotonin restoration.
References
Birdsall, T. C. (1998). 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Alternative Medicine Review, 3(4), 271–280. https://doi.org/10.1177/147323009803600103
Shaw, K., Turner, J., & Del Mar, C. (2002). Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database of Systematic Reviews, (1), CD003198. https://doi.org/10.1002/14651858.CD003198
Usage Instructions
- Take 5-HTP on an empty stomach for optimal absorption.
- It is best taken 30–60 minutes before bedtime to promote restful sleep or earlier in the day to support mood and anxiety relief.
- Avoid taking it alongside high-protein meals, which may reduce its effectiveness.
Dosage Information
For mood support:
- 50–100 mg, 1–2× daily
For sleep enhancement:
- 100–200 mg before bed
For appetite control:
- 100 mg 30 minutes before meals
Do not exceed 300 mg per day without medical guidance
Use for 6–12 weeks, then reassess or take a short break
Important Warnings
- Do not combine with SSRIs, MAOIs, or other antidepressants without medical supervision
- Avoid during pregnancy or breastfeeding
- Possible side effects: nausea, vivid dreams, or drowsiness
- Start with the lowest effective dose to assess tolerance
- Not recommended for individuals with bipolar disorder or serotonin syndrome history
Key Ingredients
5-Hydroxytryptophan
Not sure about the right dosage?
Use our Peptide Dosage Calculator for optimal application