Alarelin is a synthetic version of a natural hormone called GnRH (gonadotropin-releasing hormone). This hormone normally comes from the brain and plays a central role in controlling fertility and hormone levels by telling the pituitary gland to release LH (luteinizing hormone) and FSH (follicle-stimulating hormone). These two, in turn, regulate testosterone, estrogen, and the entire reproductive system. Alarelin was originally developed for reproductive management in animals, but it’s also widely used in research on fertility support, hormone cycle regulation, and temporary hormone suppression.

What the Science Says — Explained Simply

• Boosting Fertility Hormones-Researchers in Japan tested how Alarelin affects hormone release in rat pituitary cells. The results showed that Alarelin caused a strong increase in LH and FSH levels, just like natural GnRH would.This means Alarelin can effectively stimulate the body’s fertility hormones.

• Timing Ovulation-In another study, scientists gave Alarelin to female sheep to control ovulation and synchronize estrus (the equivalent of the menstrual cycle). The treatment worked well, helping to precisely time ovulation. This supports the use of Alarelin to regulate reproductive cycles — in animals and potentially in assisted fertility applications.

• Suppressing Hormones (on Purpose) -A landmark review from Harvard researchers explained that when GnRH-like compounds (like Alarelin) are given continuously, they first stimulate hormones, but soon turn off the receptor system. This causes temporary suppression of LH, FSH, and sex hormones like testosterone and estrogen.This effect is useful in treating hormone-related conditions like endometriosis, PCOS, or hormone-sensitive cancers.