Folistatin 344

Name: Folistatin 344
Brand: Peptalon
SKU: PE-0259-01-1
Availability: InStock
Rating: 4.8 (127 reviews)

Follistatin is a powerful myostatin and activin A inhibitor that allows for unrestricted muscle growth by suppressing natural inhibitors of muscle development. It enables rapid increases in size, strength, and lean mass.

From AED 300.00

format:

Key Ingredients

Follistatin 344

Releases genetic growth brakes

Muscle Building Support

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

Follistatin is a naturally occurring binding protein that regulates muscle growth by inhibiting myostatin and activin A, both of which limit muscle cell development. In peptide form, Follistatin allows for dramatic increases in muscle mass and density**, with minimal interference in hormonal pathways. It is considered one of the strongest non-hormonal anabolic agents, particularly in cycles aimed at breaking genetic muscle plateaus.

Follistatin is best used in short, high-impact cycles and should be approached with respect due to its strong, systemic effects on growth regulation.

Key Benefits

Suppresses myostatin and activin A
Promotes unrestricted muscle hypertrophy
Non-hormonal, does not affect testosterone or estrogen
Useful in body recomposition or extreme mass phases
Suitable for advanced users only

Scientific Background

Follistatin 344 is a synthetic version of a naturally occurring human protein called follistatin, which plays a key role in regulating muscle growth, inflammation, and tissue repair. Its most notable function is its ability to bind and neutralize myostatin — a protein that normally acts as a “brake” on muscle development.By inhibiting myostatin, Follistatin 344 removes one of the main biological limits to muscle hypertrophy. In animal models, this has led to dramatic increases in lean muscle mass, along with improved strength and physical performance (Lee & McPherron, 2001). These effects have made Follistatin 344 a subject of intense interest in both sports performance and muscle-wasting disease research.

Follistatin does not only target myostatin. It also interacts with other members of the TGF-β (transforming growth factor-beta) superfamily, such as activin A, which is involved in inflammation, fibrosis, and reproductive hormone regulation. This broader activity gives Follistatin potential beyond muscle growth — including in anti-fibrotic, fertility, and longevity-related applications.In a widely cited mouse study, systemic administration of Follistatin 344 led to up to 117% increase in muscle mass, without affecting heart or organ size, suggesting tissue-specific anabolic effects (Gilson et al., 2009). These findings have fueled its reputation as one of the most promising myostatin inhibitors available in experimental use.

In summary, Follistatin 344 research suggests benefits such as:

Increased muscle growth via myostatin suppression
Potential support in muscle wasting conditions (cachexia, sarcopenia)
Regulation of inflammatory and fibrotic pathways
Exploration in hormonal and fertility support research

References

Lee SJ, McPherron AC. Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci USA. 2001;98(16):9306–9311. [PMID: 11459935]
Gilson H. et al. Follistatin induces muscle hypertrophy through satellite cell activation and inhibition of myostatin and activin. Am J Physiol Endocrinol Metab. 2009;297(1):E157–E164. [PMID: 19369657]
Schneyer A. et al. Follistatin: a novel regulator of the hypothalamic-pituitary-gonadal axis. Endocr Rev. 2004;25(4):661–667. [PMID: 15294885]

Usage Instructions

For full preparation and use details, refer to the leaflet provided with your vial.

Reconstitute the lyophilized powder with 1–2 ml bacteriostatic water.
Inject slowly along the vial wall and swirl gently—do not shake.
Store reconstituted solution in the refrigerator (2–8 °C) and use within 10–14 days.
Administer via subcutaneous injection (typically in the abdominal region).
Follistatin acts systemically, so site-specific injections are not required. Use sterile syringes and rotate injection sites. Do not mix with other peptides in t

Dosage Information

High-Impact Hypertrophy Protocol (Advanced Users):

Dose: 100–200 mcg daily
Cycle Length: 10–15 days max
Off-cycle: Minimum 4–6 weeks between cycles
Best stacked with: IGF-1 LR3, PEG-MGF, or GH peptides

Moderate Growth Protocol:

Dose: 100 mcg every other day
Duration: 3–4 weeks
For users seeking lean mass gain without extreme rebound effects

Because of its strong myostatin inhibition, prolonged or excessive use is not recommended.

Important Warnings

For research purposes only. Not for use without clinical supervision
Store unmixed vials at 2–8 °C, protected from light
After reconstitution, use within 10–14 days
Do not freeze the peptide
Always use bacteriostatic water for mixing
Use new sterile syringes for each injection
Monitor for potential side effects such as joint tightness, unusual muscle stiffness, or systemic fatigue
Not advised for beginners or users under 21 years of age
Avoid using during illness or active inflammation