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Kisspeptin - product image
Kisspeptin - product image
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Kisspeptin - additional product image
Kisspeptin - additional product image
Kisspeptin - additional product image
Kisspeptin - additional product image
Kisspeptin - additional product image
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Peptides Line

Kisspeptin

Kisspeptin is a naturally occurring peptide that activates the release of GnRH, which then stimulates LH and FSH — the two hormones that control testosterone production and fertility.

Key Ingredients

Kisspeptin-10 acetate

Balance Hormones

Balance Hormones

Support fertility

Support fertility

Non Hormonal Use

Non Hormonal Use

Boosts Libido

Boosts Libido

Female Friendly

Female Friendly

Boosts LH and FS release

Boosts LH and FS release

Safe and Natural

Safe and Natural

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Kisspeptin is a naturally occurring peptide that activates the release of GnRH, which then stimulates LH and FSH — the two hormones that control testosterone production and fertility.

Main Information

Kisspeptin (also known as metastin) is a hypothalamic peptide that plays a pivotal role in reproductive hormone signaling. It binds to the GPR54 receptor, which triggers the release of gonadotropin-releasing hormone (GnRH). In turn, this causes the pituitary gland to release LH and FSH, leading to endogenous testosterone production and improved fertility function.

Unlike Triptorelin, which causes hormonal shutdown after overstimulation, Kisspeptin provides a physiological “nudge” to the HPTA — making it an excellent tool for:

  • Post-cycle therapy (PCT)
  • Fertility recovery
  • Natural hormone optimization protocols
  • Restoring suppressed testosterone production

It is non-suppressive, well-tolerated, and can be used alone or stacked with HCG or SERMs like Clomid for more robust recovery protocols.

Scientific Background

Kisspeptin is a naturally occurring peptide hormone, first discovered in cancer research and later found to play a central role in reproductive health. Scientists realized that kisspeptin acts like the body’s “on-switch” for puberty and fertility, triggering the brain to release gonadotropin-releasing hormone (GnRH)—which in turn regulates LH and FSH, the key reproductive hormones.

Pharmaceutical versions of kisspeptin were developed to explore its potential in treating infertility, hormone imbalances, and even polycystic ovary syndrome (PCOS). Unlike traditional hormone therapies, kisspeptin works upstream, encouraging the body to reactivate its natural hormonal rhythms.It’s currently being tested in both men and women, with studies showing that it can boost testosterone and improve egg maturation without the side effects of stronger hormone drugs.

References

Jayasena CN, Nijher GM, Abbara A, et al. Twice-weekly kisspeptin-54 administration induces egg maturation in women undergoing IVF. J Clin Invest. 2014;124(8):3667–3677. https://doi.org/10.1172/JCI75730

Usage Instructions

To ensure safe and effective use of Peptide Products, like Kisspeptin, it’s important to follow correct preparation, handling, and injection techniques. Below is a summary of the most essential steps. For detailed guidance, please refer to the official Product Leaflet included with your vial. You can also view the the Leaflet online at the right bottom of the product page.

  • Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
  • Do not use if the solution appears cloudy, discolored, or contains particles.
  • Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
  • Reconstitute using bacteriostatic water.
  • Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
  • This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
  • Always use a new, sterile syringe and needle for every injection.
  • Maintain aseptic technique and never reuse syringes.
  • Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
  • Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
  • Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
  • Store the lyophilized powder refrigerated at 2–8 °C.
  • After reconstitution, use within 7–14 days, keeping the solution refrigerated.
  • Do not freeze. Protect from light.

Dosage Information

HPTA Restart Protocol (PCT):

  • Dose: 100–200 mcg daily
  • Cycle: 10–14 days post-cycle
  • Often used with Clomid or low-dose HCG
  • Goal: Stimulate full axis recovery without suppression

Fertility or Hormone Support:

  • Dose: 200 mcg 1× daily or EOD
  • Timing: In the morning or per fertility protocol
  • Combine with lifestyle recovery strategies for best results

Gentle Testosterone Optimization:

  • Dose: 100 mcg EOD
  • Used in off-cycle or hormone reset phases
  • Especially suitable for younger users or those avoiding suppressive agent

Important Warnings

  • For research use only – not approved for therapeutic application.
  • Store unmixed vials refrigerated (2–8 °C).
  • Once mixed, use within 10–14 days.
  • Avoid freezing.
  • Kisspeptin is non-suppressive, but improper stacking with suppressive compounds (e.g., Triptorelin, exogenous testosterone) may reduce its effectiveness.
  • Use sterile technique and rotate injection sites.
  • Generally well-tolerated with minimal side effects.

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