MT 2

Melanotan II (MT-2) is a synthetic peptide that stimulates melanin production, resulting in a darker, natural-looking tan without excessive sun exposure.

From AED 160.00

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Key Ingredients

Melanotan II acetate

Promotes Natural Tan

Controls Appetite

Boosts Libido

Protects against UV Rays

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

MT-2 (Melanotan II) is a synthetic melanocortin peptide that mimics alpha-MSH (melanocyte-stimulating hormone). It binds to MC-1 receptors in the skin to increase melanin production, leading to enhanced pigmentation (tanning) — even with minimal UV exposure. MT-2 also stimulates MC-3 and MC-4 receptors in the brain, contributing to increased libido and arousal, similar to PT-141. However, MT-2 offers a broader effect profile, combining aesthetic benefits (tanning) with mood, energy, and libido support.

Scientific Background

Melanotan II (MT-2) is a synthetic peptide developed to stimulate melanin production in the skin, effectively enhancing pigmentation and offering protection against UV damage. It is a potent analog of alpha-melanocyte-stimulating hormone (α-MSH), a natural hormone involved in skin coloration, energy balance, and even sexual arousal. MT-2 was originally synthesized in the 1990s at the University of Arizona, where researchers were seeking a pharmacological way to induce tanning without sun exposure—as a potential protective strategy against skin cancer . What makes MT-2 unique is its multifaceted mechanism of action. It primarily binds to the melanocortin-1 receptor (MC1R) found on melanocytes, the pigment-producing cells in the skin. This binding triggers increased production of eumelanin, the dark brown to black pigment that gives skin a tanned appearance and provides natural UV protection. Studies have shown that MT-2 can significantly enhance melanin density in fair-skinned individuals, allowing them to achieve a tan while reducing the need for sun exposure .

In addition to its effects on pigmentation, MT-2 has notable secondary effects through its interaction with other melanocortin receptors, especially MC3R and MC4R. These receptors are involved in energy regulation, appetite control, and sexual function. As a result, some users report suppressed appetite, enhanced libido, and increased sexual arousal as secondary benefits. These effects were so pronounced in early trials that they led to the development of Bremelanotide (PT-141), a derivative of MT-2 now approved for treating hypoactive sexual desire disorder in women .From a biochemical standpoint, MT-2 is also appreciated for its stability and long half-life compared to natural α-MSH, making it suitable for intermittent subcutaneous injection rather than continuous dosing.

Key Benefits Backed by Research

Increased tanning and UV protection: Clinical studies show enhanced pigmentation and reduced sunburn risk with MT-2 use .
Potential appetite suppression: Observed reduction in food intake in some subjects, likely due to MC3/MC4 receptor interaction.
Increased libido and erectile response: Shown in early trials for erectile dysfunction and sexual arousal disorders .

These combined effects make MT-2 a popular compound in aesthetic, wellness, and biohacking communities seeking UV-free tanning, photo-protection, and even enhanced vitality—though its use remains off-label and research-based in most regions.

References

Hadley ME, Dorr RT. Melanocortin peptides for the treatment of obesity and sexual dysfunction. Curr Top Med Chem. 2006;6(6):581–595. doi: 10.2174/156802606776287274
Dorr RT, Dvorakova K, Brooks C, et al. Effects of an alpha-melanocyte stimulating hormone analog on tanning in humans. Arch Dermatol. 2000;136(4):432–438. doi: 10.1001/archderm.136.4.432
Wessells H, Gralnek D, Dorr R, et al. Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction. Urology. 2000;56(4):641–646. doi: 10.1016/S0090-4295(00)00678-3

Usage Instructions

To ensure safe and effective use of Peptide Products, like Ipamorelin, it’s important to follow correct preparation, handling, and injection techniques. Below is a summary of the most essential steps. For detailed guidance, please refer to the official Product Leaflet included with your vial. You can also view the the Leaflet online at the right bottom of the product page.

Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.Do not freeze. Protect from light.

Dosage Information

Tanning / Pigmentation Protocol:

Loading Phase: 250–500 mcg per day for 10–14 days
Continue minimal sun exposure to activate melanogenesis
Maintenance Phase: 250 mcg 1–3× per week to maintain tan

Libido / Sexual Wellness Use:

Dose: 500–1000 mcg as needed (prior to intimacy)
May cause flushing, appetite loss, or light nausea initially
Can be alternated or stacked with PT-141 for enhanced effect

Important Warnings

For research or cosmetic use only – not approved for human medical reatment
Store unmixed vial at 2–8 °C
Once mixed, use within 7–14 days
May cause darkening of moles, freckles, or skin tone changes — monitor pigmentation
Avoid use during pregnancy or active melanoma risk
Initial side effects may include nausea, facial flushing, or appetite suppression
Do not exceed 2 mg per day