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Oxytocin
Oxytocin is a natural neuropeptide that promotes social bonding, emotional connection, and trust.
Key Ingredients
Oxytocin Acetate
Not sure about the right dosage?
Use our Peptide Dosage Calculator for optimal application
Main Information
Oxytocin is a naturally occurring peptide hormone produced in the hypothalamus and secreted by the posterior pituitary gland. It plays a central role in social bonding, trust, intimacy, and emotional attunement. While it is best known for roles in childbirth and lactation, exogenous (external) Oxytocin — especially in nasal spray form — is increasingly used in neurosupportive and intimacy-enhancingcontexts.Oxytocin affects key brain areas such as the amygdala and ventral striatum, reducing social anxiety, improving emotional empathy, and facilitating couples’ connection and sexual receptivity. It’s also being studied for its effects on autism spectrum disorders, PTSD, emotional trauma, and even appetite modulation.
Scientific Background
Oxytocin is a naturally occurring neuropeptide and hormone, produced in the hypothalamus and secreted by the posterior pituitary gland. Best known for its roles in childbirth, lactation, and bonding, oxytocin has recently gained attention for its powerful effects on social behavior, emotional regulation, and stress resilience.Originally studied for its role in uterine contractions and milk let-down, oxytocin is now recognized as a central neuromodulator that influences trust, empathy, emotional memory, and interpersonal connection. It exerts its effects through oxytocin receptors widely distributed in the brain, particularly in the amygdala, hippocampus, and nucleus accumbens—areas involved in emotion and reward.
What makes oxytocin unique is its dual action: it works both peripherally as a hormone (e.g., during labor), and centrally in the brain to modulate mood, attachment, and fear responses. Research shows that intranasal oxytocin can enhance social cognition, reduce anxiety, and even improve emotional communication in conditions like autism and PTSD .Its ability to regulate stress pathways, promote feelings of safety, and enhance parasympathetic activity has led to its use in protocols aimed at emotional trauma recovery, interpersonal therapy, and even sexual wellness.
References
Heinrichs M, Domes G. Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans. Prog Brain Res. 2008;170:337–350. doi: 10.1016/S0079-6123(08)00428-7
MacDonald K, MacDonald TM. The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans. Harv Rev Psychiatry. 2010;18(1):1–21. doi: 10.3109/10673220903523615
Usage Instructions
Oxytocin is most commonly administered via nasal spray, allowing for rapid delivery to the brain through the olfactory pathway.
- Shake bottle gently before use
- Administer 1–2 sprays per nostril, up to 1–2× daily
- Timing: 15–30 minutes before desired emotional or relational effects (e.g., social situations, therapy, intimacy)
- Store in refrigerator (2–8 °C) when not in use
- Do not exceed dosage or frequency unless advised
Dosage Information
Emotional Bonding / Social Support:
- Dose: 20–40 IU (1–2 sprays per nostril)
- Use 15–30 minutes before desired effect
- Ideal for couples, therapy sessions, or group dynamics
Sexual Wellness Protocol:
- Dose: 20–60 IU pre-intimacy
- May be used alongside PT-141 for amplified arousal and receptivity
- Supports trust, physical connection, and sexual satisfaction
Anxiety / Stress Support:
- Dose: 10–20 IU as needed
- Use in emotionally triggering environments or as part of PTSD / burnout protocols
Important Warnings
- For research or investigational use only – not approved for general pharmaceutical application.
- Store refrigerated (2–8 °C). Do not freeze.
- Do not share nasal applicator with others.
- Do not use in individuals with hypersensitivity to hormone therapy, or unstable mental health conditions without professional supervision.
- May cause temporary headache, flushing, or emotional intensification. Avoid repeated use without breaks to reduce tolerance.
- Not intended as a replacement for relationship therapy or psychological care.
Oxytocin
Oxytocin is a natural neuropeptide that promotes social bonding, emotional connection, and trust.
Key Ingredients
Oxytocin Acetate
Not sure about the right dosage?
Use our Peptide Dosage Calculator for optimal application