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Selank
Selank improves focus, memory, and emotional stability—without sedation or addiction risk.
Key Ingredients
Selank Acetate
Not sure about the right dosage?
Use our Peptide Dosage Calculator for optimal application
Main Information
Selank is a synthetic heptapeptide derived from the naturally occurring immune system peptide Tuftsin, and designed to enhance mental performance, neuroprotection, and stress resilience. It modulates the GABAergic system—the same pathway affected by benzodiazepines—but does so without sedation, dependency, or cognitive blunting. Used as a nasal spray or injectable, Selank crosses the blood-brain barrier and supports emotional regulation, cognitive performance, and immune system modulation. It’s particularly valued for those facing stress-induced burnout, anxiety, or high cognitive demands. Selank is non-hormonal, non-addictive, and suitable for men and women across wellness, productivity, and recovery protocols.
Scientific Background
SELANK is a synthetic neuropeptide nootropic derived from Tuftsin, a natural peptide involved in immune modulation. Originally developed by the Institute of Molecular Genetics (Russian Academy of Sciences) as a non-sedating anxiolytic, SELANK has since been studied for its broad neuroprotective, cognitive, and immune-regulating properties.
How SELANK Works
Neurotransmitter Modulation - SELANK enhances serotonin, dopamine, and GABA balance—improving mood, focus, and reducing anxiety without sedation. It also regulates norepinephrine, supporting mental resilience under stress. Its anxiolytic effect has been shown to be comparable to benzodiazepines, but without the side effects or dependency risk.
BDNF Expression & Neuroplasticity - SELANK increases brain-derived neurotrophic factor (BDNF), a key protein for learning, memory, and neural regeneration, making it effective during burnout, emotional fatigue, or post-illness recovery .Immune and Inflammatory Balance -As a Tuftsin analog, SELANK also modulates the immune system—reducing pro-inflammatory cytokines like IL-6 and TNF-alpha, while supporting antiviral defenses. This makes it especially useful during chronic stress, fatigue syndromes, or overtraining recovery.
What Makes SELANK Unique
- Targets GABA, serotonin, and dopamine systems simultaneously
- Fast-acting, non-sedating anxiolytic with no dependency risk
- Enhances mental clarity, stress adaptation, and immune function
- Delivered via nasal spray or subcutaneous injection for rapid CNS effects
Ideal for individuals facing burnout, anxiety, cognitive fatigue, or immunosuppression under chronic stress.
References
Andreeva LA, et al. The anxiolytic effects of Selank in the treatment of generalized anxiety disorder. Zh Nevrol Psikhiatr Im S S Korsakova. 2007;107(10):38–43. PMID: 18159778
Yatskin ON, et al. Selank increases BDNF expression in rat hippocampus after stress. Bull Exp Biol Med. 2011;150(5):598–600. doi: 10.1007/s10517-011-1165-0
Kolomin T, et al. Immunomodulatory properties of Selank and Tuftsin in in vitro and in vivo models. J Mol Neurosci. 2016;58(2):277–284. doi: 10.1007/s12031-015-0615-3
Usage Instructions
- Selank is typically administered as a nasal spray, which allows for fast CNS delivery.
- Always follow your product-specific instructions.
- Prime spray bottle before first use
- Administer 1–2 sprays per nostril, up to 2–3× daily
- Use in the morning, pre-task, or pre-sleep depending on goal
- Do not exceed the recommended dose
- Refrigerate between uses (2–8 °C) if instructed
- Injectable forms are administered subcutaneously at low doses.Please refer to the leaflet delivered with your product for furher information on preperation and use of Selank.
Dosage Information
Cognitive Support / Focus Protocol:
- Dose: 250–500 mcg per dose
- Frequency: 1–2× daily
- Duration: 10–30 days, then pause or cycle
- Use before tasks requiring focus, memory, or calm under pressure
Anxiety / Stress Relief Protocol:
- Dose: 300–600 mcg per day
- Timing: Morning + late afternoon
- Can be taken daily or situationally (e.g., before stress exposure)
Immunomodulation Support:
- Dose: 400 mcg daily
- Duration: 7–14 days during periods of immune challenge or chronic fatigue
Important Warnings
- For research use only – not approved as a prescription drug.
- Store nasal spray refrigerated (2–8 °C) when not in use.
- Do not freeze.
- Do not share nasal applicators.
- Selank is well tolerated. Possible minor effects may include mild nasal dryness, transient headache, or light fatigue in high doses.
- No known addiction risk, hormonal disruption, or sedation.
- Use only as directed.
- Discontinue if adverse effects occur.
Selank
Selank improves focus, memory, and emotional stability—without sedation or addiction risk.
Key Ingredients
Selank Acetate
Not sure about the right dosage?
Use our Peptide Dosage Calculator for optimal application