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Peptides Line

TB500

Name: TB500
Brand: Peptalon
SKU: PE-0011-01-10
Availability: InStock
Rating: 4.8 (127 reviews)

TB-500 is a synthetic version of Thymosin Beta-4, known for its ability to accelerate tissue repair, reduce inflammation, and support systemic recovery.

From AED 250.00

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Key Ingredients

Thymosin Alpha

Speeds Up Healing

Boosts Recovery

Protects Joints and Tendons

Improves Blood Supply

Heals Gut Lining 01

Enhances Mobility

Anti inflammatory

Safe and Natural

Improves Blood Supply

Safe For Prolongued Use

Supports Tissue And Fibre Repair

Supports Healthy Aging

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

TB-500 is a synthetic form of Thymosin Beta-4, a naturally occurring peptide involved in tissue regeneration, inflammation control, and cell repair. It works by regulating actin, a protein essential for cell movement and healing. Unlike localized peptides, TB-500 offers systemic effects, promoting faster recovery across multiple tissues—including muscles, tendons, ligaments, skin, and even internal organs. It also supports angiogenesis (new blood vessel formation), making it especially valuable in post-injury or post-surgical protocols.

Who is it for?

TB-500 is ideal for those recovering from physical strain, injury, or surgery, as well as athletes or high performers aiming to improve recovery speed, resilience, and overall repair capacity.

Scientific Background

From Discovery to Regeneration Powerhouse

TB500 is the synthetic peptide version of Thymosin Beta-4 (Tβ4) — a naturally occurring protein first discovered in the 1970s within thymic extracts linked to immune development and tissue healing. Early research showed its unique potential in accelerating recovery and regeneration, setting the stage for decades of clinical interest.

The Secret Lies in Actin Dynamics

At the heart of TB500’s effects is its ability to regulate actin, a key protein that drives cell movement, tissue repair, and the formation of new blood vessels. By binding to G-actin, TB500 orchestrates the cellular “construction crew,” ensuring tissues heal faster, stronger, and with better structural integrity.

Why It Matters for Healing & Performance

This peptide doesn’t just patch things up — it promotes real regeneration.

• Faster Muscle & Tendon Recovery: Helps repair microtears and injuries without leaving stiff scar tissue.

• Stronger Connective Tissues: Supports collagen alignment for long-term joint health.

• Enhanced Circulation: Stimulates angiogenesis for improved nutrient delivery.

• Anti-Inflammatory Effects: Lowers IL-6 and TNF-α, reducing pain and swelling.

From Clinical Studies to Real-World Use

Initially studied for heart repair and corneal healing, TB500 has since moved into performance medicine, sports injury recovery, and post-surgical protocols. Its unique ability to regenerate without fibrosis has made it a go-to option for athletes, biohackers, and rehabilitation specialists alike.

References

Goldstein AL, Hannappel E, Kleinman HK. Thymosin β4: actin-sequestering protein moonlighting as a regulator of angiogenesis and tissue regeneration. Expert Opin Biol Ther. 2005;5(5):593–602. doi: 10.1517/14712598.5.5.593
Sosne G et al. Thymosin beta 4 promotes corneal wound healing and modulates inflammation. FASEB J. 2002;16(10):1231–1233. doi: 10.1096/fj.01-0983fje

Usage Instructions

To ensure safe and effective use of Peptide Products, like TB500, it’s important to follow correct preparation, handling, and injection techniques. Below is a summary of the most essential steps. For detailed guidance, please refer to the official Product Leaflet included with your vial. You can also view the the Leaflet online at the right bottom of the product page.

Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Injury Recovery / Post-Surgical Healing

Dosage: 2.0–2.5 mg twice weekly
Duration: 4–6 weeks (loading phase), followed by maintenance
Often combined with BPC-157 for synergistic healing

Chronic Inflammation / Joint Support

Dosage: 2.0 mg once weekly
Duration: Ongoing or as needed during flare-ups
Can be cycled in 6-week intervals with rest periods

Performance & General Recovery Optimization

Dosage: 1.5–2.0 mg weekly
Duration: 4–8 weeks during intense training or recovery phases
Supports systemic repair and resilience

Important Warnings

Warnings & Storage Guidelines

Store lyophilized powder in the fridge (2–8 °C)
After reconstitution, refrigerate and use within 10–14 days
Do not freeze
Use only bacteriostatic water
Avoid injecting near open wounds or infected areas
Never reuse needles or syringes
If irritation or systemic symptoms occur, discontinue use and seek guidance

Frequently Asked Questions

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Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Injury Recovery / Post-Surgical Healing

Dosage: 2.0–2.5 mg twice weekly
Duration: 4–6 weeks (loading phase), followed by maintenance
Often combined with BPC-157 for synergistic healing

Chronic Inflammation / Joint Support

Dosage: 2.0 mg once weekly
Duration: Ongoing or as needed during flare-ups
Can be cycled in 6-week intervals with rest periods

Performance & General Recovery Optimization

Dosage: 1.5–2.0 mg weekly
Duration: 4–8 weeks during intense training or recovery phases
Supports systemic repair and resilience

Important Warnings

Warnings & Storage Guidelines

Store lyophilized powder in the fridge (2–8 °C)
After reconstitution, refrigerate and use within 10–14 days
Do not freeze
Use only bacteriostatic water
Avoid injecting near open wounds or infected areas
Never reuse needles or syringes
If irritation or systemic symptoms occur, discontinue use and seek guidance

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TB500