Tesamorelin

Tesamorelin is a synthetic GHRH analog that stimulates natural growth hormone release, with proven effects on reducing visceral (abdominal) fat.

From AED 240.00

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Fat Burning Support

Supports Muscle during deficit

Growth Hormone Optimization

Visceral Fat Reduction

Improves Metabolism

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Main Information

Tesamorelin is a highly stable, long-acting analog of Growth Hormone Releasing Hormone (GHRH 1–44) that stimulates the pituitary to secrete endogenous growth hormone (GH) in a controlled, pulsatile manner. Uniquely among GHRH peptides, Tesamorelin has FDA approval for reducing visceral adipose tissue (VAT) — a key marker of cardiometabolic risk.Tesamorelin’s effects extend beyond GH stimulation: it helps repartition body fat, improve lipid metabolism, and support abdominal fat loss, particularly in the presence of hormonal dysregulation or age-related GH decline. Unlike standard GH therapy, Tesamorelin works with the body’s hormonal feedback systems and is considered HPTA-friendly.

Scientific Background

Tesamorelin is a stabilized synthetic analogue of Growth Hormone–Releasing Hormone (GHRH 1–44), developed through recombinant DNA technology to mimic endogenous GHRH with improved half-life and receptor stability. Originally designed to treat HIV-associated lipodystrophy, it was FDA-approved in 2010 after demonstrating significant reductions in visceral adipose tissue (VAT)—a key predictor of metabolic and cardiovascular risk.Tesamorelin binds to GHRH receptors in the anterior pituitary, stimulating pulsatile GH release while preserving the body’s natural feedback mechanisms—in contrast to exogenous GH, which suppresses endogenous production. This triggers a rise in Insulin-like Growth Factor 1 (IGF-1) and initiates a cascade of anabolic and lipolytic effects.Benefits include:

Enhanced lipolysis, especially in deep abdominal fat depots

Increased IGF-1, promoting tissue repair, collagen synthesis, and muscle tone

Improved insulin sensitivity, glucose metabolism, and lipid profile [1][2]

Tesamorelin is now widely explored in anti-aging, body recomposition, and metabolic reset protocols, where visceral fat reduction and GH axis optimization are priorities. Ideal for use in cutting cycles, GH therapy support, or targeted visceral fat loss in high-risk individuals.

References

Falutz J et al. Effects of Tesamorelin in HIV-infected patients with abdominal fat accumulation. J Clin Endocrinol Metab. 2007;92(6):2074–2081. doi: 10.1210/jc.2006-2705
Guaraldi G et al. Tesamorelin for visceral fat reduction in HIV: a review and clinical perspective. Ther Adv Chronic Dis. 2020;11:2040622320931571. doi: 10.1177/2040622320931571

Usage Instructions

To ensure safe and effective use of Peptide Products, like Tesamorelin, it’s important to follow correct preparation, handling, and injection techniques. Below is a summary of the most essential steps. For detailed guidance, please refer to the official Product Leaflet included with your vial. You can also view the the Leaflet online at the right bottom of the product page.

Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Clinically Validated (Fat Loss & VAT Reduction):
Dose: 2 mg once daily, subcutaneously
Timing: Evening, fasted state preferred
Cycle Length: Minimum 12–16 weeks for measurable effects
Used in lipodystrophy, abdominal obesity, or anti-aging protocols

Wellness / Recomposition Use:
Dose: 1–2 mg daily
Best results when combined with GH-supportive lifestyle (training, sleep, insulin management)

Stacking Recommendations:
Can be used alone or stacked with Ipamorelin or CJC-1295 (no DAC)
Often combined with fat-burning or mitochondrial peptides in advanced stacks

Important Warnings

For research use only – not approved for general GH replacement. Store unmixed vials refrigerated (2–8 °C).
Use only bacteriostatic water to reconstitute. After mixing, solution must be used within 10–14 days.
Do not freeze.
Tesamorelin is generally well tolerated. May cause temporary injection site redness, water retention, or mild bloating in early use.
Avoid use in individuals with active cancer or untreated endocrine disorders.
Use sterile syringes and rotate injection areas to prevent irritation.
Consult a qualified practitioner for extended use or if combining with other compounds.